Mesothelioma

Malignant Mesothelioma At a Glance
By James Howell

Malignant mesothelioma (cancer of the mesothelium) is a disease in which cells of the mesothelium become abnormal and divide without control or order. It is a rare form of cancer that most frequently arises from the cells lining the sacs of the chest (the pleura) or the abdomen (the peritoneum). Malignant mesothelioma is closely linked to exposure to asbestos – a natural fiber that was once used in manufacturing a wide variety of industrial and household products. Workers involved in asbestos mining, milling and manufacturing are at the greatest risk for developing malignant mesothelioma. Also at high risk are shipyard workers, workers in the heating and construction industries, and other tradespeople. Family members and others living with asbestos workers have an increased risk of developing malignant mesothelioma, and possibly other asbestos related diseases as well. Cases of malignant mesothelioma have even included people whose only exposure was breathing the air through ventilation systems.

Although reported incidence rates have increased in the past 20 years, malignant mesothelioma is still a relatively rare cancer. Between 1973 and 1984, there has been a threefold increase in the diagnosis of pleural mesothelioma in Caucasian males. From 1980 to the late 1990s, the death rate from malignant mesothelioma in the USA increased from 2,000 per year to 3,000, with men four times more likely to acquire it than women. The actual rates may be even higher however, since it is possible that many cases of malignant mesothelioma are misdiagnosed as adenocarcinoma of the lung, which is difficult to differentiate from mesothelioma.

The average age of diagnosis of malignant mesothelioma is 60. The average survival time varies from 4 to 18 months, and death is usually due to infection or respiratory failure from the progression of the mesothelioma.

Find out more about Malignant Mesothelioma.

Or learn more about Mesothelioma Cancer.

By Robert Linebaugh

Mesothelioma, the deadly disease which has topped news headlines for the last decade, is contracted through exposure to airborne fibers of asbestos. Sadly, the under-regulation of asbestos usage in years past, and arguably still today, exposed millions to airborne fibers and as a result thousands contracted the disease.

It can be safely said that almost everyone in the world has been exposed to asbestos in varying degrees. Because of the unique nature of the disease, even those who have suffered only minimal exposure are at risk of contracting the disease. In effect, virtually everyone has some risk of contracting Mesothelioma.

But this sort of statement perhaps oversteps the bounds of rationality. While it is certainly true that individuals who have been exposed to small amounts of asbestos for relatively short periods of time have contracted the disease, this is a rarity rather than a regularity. In fact, the vast majority of Mesothelioma cases involve individuals who were exposed to airborne asbestos fibers for intense and extended periods of time.

The industries most in danger of prolonged exposure and thus of contraction are shipbuilding trades, asbestos mining and milling, textile manufacturing, insulation work in construction, and brake repair personnel. There are, however, some other minor factors which can affect the likelihood of contracting the disease. Among these is radiation exposure. There have been causes in which individuals who were exposed to radiation have subsequently displayed signs of and ultimately contracted mesothelioma. However, empirical studies to attempt to verify this correlation have not proven out this claim very strongly.

Another more certain cause of the disease was the taking of the Polio vaccine between 1955 and 1963. Some batches of this vaccine were contaminated with Simian Virus 40 which has been detected in a host of rare cancers including Mesothelioma.

Those involved in construction or who lived in homes in the Cappadocian region of Turkey are also particularly at risk. In this region, homebuilders used Erionite, which is a type of zeolite silica stone. Exposure to the fibrous strands of this building material have led to an annual death rate of roughly 1% of the population which dies of mesothelioma each year in Turkey.

One of the most influential factors affecting Mesothelioma contraction is genetics. Some individuals who have been exposed to long periods and high quantities of asbestos have not contracted the disease. As a result, doctors have concluded that genetics play a major role in determining whether or not patients contract the disease. Unfortunately, the gene variability which offers some resistance to the disease also means that some are particularly vulnerable to asbestos exposure.

Robert Linebaugh writes about health issues, and focuses on mesothelioma. Learn more at http://www.justmeso.com.