While the tumors of mesothelium was initially recognized in late 18th century, and was more examined till middle of 20th century. It was during this time when uncertainties of the causal relationship of cancer with the asbestos removal became highly substantiated. The joint venture of research through Department of Thoracic Surgery at University of Wits water along with Johannesburg General Hospital of South Africa offered the most convincing evidence of nexus between the exposure of asbestos and development of the pleural mesothelioma.
However, Mesothelioma is the aggressive cancer which affects the lining membrane of abdomen and lungs. Malignant mesothelioma is considered to be most serious of all the diseases related to asbestos. The primary and key cause along with the risk factor for the mesothelioma is certainly the exposure to asbestos.
However, making the correct diagnosis of mesothelioma is specifically difficult for the doctors since the disease usually presents with the symptoms which mimic various other common sicknesses. There is also no known treatment or therapy for mesothelioma, however treatments like chemotherapy and surgery has also helped to enhance the specific prognosis of mesothelioma.
Pleural mesothelioma which affects the protective lining of the lung in chest cavity also represents about 3 quarters of every incidence of mesothelioma. Peritoneal mesothelioma, also affects the cavity of abdominal, and the pericardial mesothelioma that affects cardiac cavity which comprises of the remainder.
Moreover, there are 3 recognized cell-types of mesothelioma. While the prognosis is usually poor, it is even considered to be less aggressive than the biphasic mesothelioma and sarcomatoid mesothelioma, which comprises the remainder of diagnoses of various cell types.
The cavities in body surrounding the abdomen, heart and chest are surrounded by the membrane of the cells known as mesothelium. Moreover, Mesothelial cells help in general functions of the organ. The mesothelium is chiefly significant to the organs which are usually in motion, like the contractions and expansion of the lungs, heart and stomach.